BDBM50352949 CHEMBL1824917

SMILES Clc1ccccc1C(=O)Nc1ccc(cc1)-c1ccnc(n1)-c1ccccc1

InChI Key InChIKey=CPKGJKXYTLNLMB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50352949   

TargetSmoothened homolog(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50352949(CHEMBL1824917)
Affinity DataIC50:  27nMAssay Description:Antagonist activity at human SMO expressed in HEPM cells assessed as reduction of GLI expression after 24 hrs by Quantigene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed