BDBM50353747 CHEMBL561013::JWH-018

SMILES CCCCCn1cc(C(=O)c2cccc3ccccc23)c2ccccc12

InChI Key InChIKey=JDNLPKCAXICMBW-UHFFFAOYSA-N

Data  18 KI  1 IC50  2 Kd  9 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50353747   

TargetCannabinoid receptor 1/2(Rattus norvegicus (Rat))
Biological Research Centre Of The Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50353747(CHEMBL561013 | JWH-018)
Affinity DataEC50:  36nMAssay Description:Agonist activity at CB1R/CB2R in Wistar rat brain membranes after 60 mins by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50353747(CHEMBL561013 | JWH-018)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human CB1 receptor expressed in mouse AtT20 cells incubated for 60 mins by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
West Virginia University

Curated by ChEMBL
LigandPNGBDBM50353747(CHEMBL561013 | JWH-018)
Affinity DataEC50:  7.30nMAssay Description:Agonist activity at CB2 receptor (unknown origin) expressed in human HEK293T cells co-expressing beta-arrestin2 assessed as beta-arrestin2 recruitmen...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
West Virginia University

Curated by ChEMBL
LigandPNGBDBM50353747(CHEMBL561013 | JWH-018)
Affinity DataEC50:  22nMAssay Description:Agonist activity at human CB2 receptor expressed in mouse AtT20 cells incubated for 60 mins by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
West Virginia University

Curated by ChEMBL
LigandPNGBDBM50353747(CHEMBL561013 | JWH-018)
Affinity DataEC50:  22nMAssay Description:Agonist activity at human CB2 receptor expressed in mouse AtT20 cells incubated for 60 mins by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50353747(CHEMBL561013 | JWH-018)
Affinity DataEC50:  35nMAssay Description:Agonist activity at CB1 receptor (unknown origin) expressed in human HEK293T cells co-expressing beta-arrestin2 assessed as beta-arrestin2 recruitmen...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50353747(CHEMBL561013 | JWH-018)
Affinity DataEC50:  36nMAssay Description:Agonist activity at CB1 receptor (unknown origin) expressed in human HEK293T cells co-expressing beta-arrestin2 assessed as beta-arrestin2 recruitmen...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
West Virginia University

Curated by ChEMBL
LigandPNGBDBM50353747(CHEMBL561013 | JWH-018)
Affinity DataEC50:  7.20nMAssay Description:Agonist activity at CB2 receptor (unknown origin) expressed in human HEK293T cells co-expressing beta-arrestin2 assessed as beta-arrestin2 recruitmen...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50353747(CHEMBL561013 | JWH-018)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human CB1 receptor expressed in mouse AtT20 cells incubated for 60 mins by FLIPR membrane potential assayMore data for this Ligand-Target Pair
In DepthDetails PubMed