BDBM50354779 CHEMBL1834330

SMILES Nc1c(F)c(NCCNc2ccccn2)c2OCC3(CCCC3)n3cc(C(O)=O)c(=O)c1c23

InChI Key InChIKey=WAYOWHQFYFTAPH-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50354779   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50354779(CHEMBL1834330)
Affinity DataEC50:  2.00E+4nMAssay Description:Inhibition of GSK3-beta in human HepG2 cells assessed as incorporation of [3H]glucose into glycogen after 3 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50354779(CHEMBL1834330)
Affinity DataIC50:  12nMAssay Description:Inhibition of human recombinant full length GSK3beta after 1 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed