BDBM50355460 CHEMBL1835557

SMILES Cc1nc2ccccc2n1Cc1ccc(cn1)C(=O)N[C@@H]1CCCC[C@@H]1C(=O)NO

InChI Key InChIKey=LHYOTWUSFMELDU-ZWKOTPCHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50355460   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Sun Pharma Advanced Research

Curated by ChEMBL
LigandPNGBDBM50355460(CHEMBL1835557)
Affinity DataIC50:  126nMAssay Description:Inhibition of TACE in human whole blood assessed as reduction of of LPS-induced TNFalpha production pretreated 15 mins before LPS challenge measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed