BDBM50355463 CHEMBL1835560

SMILES ONC(=O)[C@H]1CCC[C@H]1NC(=O)c1ccc(Cn2c(nc3ccccc23)C(F)(F)F)nc1

InChI Key InChIKey=AHNMTSUUYUMNIJ-LSDHHAIUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50355463   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Sun Pharma Advanced Research

Curated by ChEMBL
LigandPNGBDBM50355463(CHEMBL1835560)
Affinity DataIC50:  74nMAssay Description:Inhibition of TACE in human whole blood assessed as reduction of of LPS-induced TNFalpha production pretreated 15 mins before LPS challenge measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed