BDBM50356677 CHEMBL1917592
SMILES CCCS(=O)(=O)c1ccc(F)c(c1)C#Cc1cc(Cl)ccc1OCC(O)=O
InChI Key InChIKey=FLVRGQWJTKWGBU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50356677
Affinity DataKi: 0.370nMAssay Description:Displacement of [3H]PGD2 from mouse CRTH2 expressed in human HEK cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Antagonist activity human CRTH2 expressed in chinese hamster CHO cells assessed as inhibition of PGD2-induced [35S]GTPgamma binding by liquid scintil...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Antagonist activity at human CRTH2 expressed in human CHO cells by cellular dielectric spectroscopyMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Antagonist activity at CRTH2 in human blood cells assessed as inhibition of PGD2-induced eosinophil cell shape change after 10 mins by flow cytometryMore data for this Ligand-Target Pair