BDBM50357460 CHEMBL1917729

SMILES Nc1cc(ccn1)C(=O)NC1c2ccccc2-c2c1cccc2-c1nc2ccncc2[nH]1

InChI Key InChIKey=MLQIPNRXDPWOES-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50357460   

TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research And Development

Curated by ChEMBL

LigandBDBM50357460(CHEMBL1917729)Copy SMILESCopy InChI

Affinity DataIC50:  900nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI