BDBM50358252 CHEMBL1922235

SMILES COc1ccc(cc1)C(=O)Nc1cccc(O)c1NC(=O)c1ccc(cc1)N1CCCN(C)CC1

InChI Key InChIKey=IJNIQYINMSGIPS-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50358252   

TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50358252(CHEMBL1922235)
Affinity DataKi:  31nMAssay Description:Inhibition of human factor 10A using chromogenic substrate S2222 by dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50358252(CHEMBL1922235)
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition of human plasma kallikrein using chromogenic substrate S2302 by dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50358252(CHEMBL1922235)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human thrombin using chromogenic substrate S2238 by dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1A10(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50358252(CHEMBL1922235)
Affinity DataKi:  2.35E+5nMAssay Description:Inhibition of human recombinant UGT1A10 after 10 mins in presence of UDPGAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1A8(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50358252(CHEMBL1922235)
Affinity DataKi:  3.54E+5nMAssay Description:Inhibition of human recombinant UGT1A8 after 10 mins in presence of UDPGAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50358252(CHEMBL1922235)
Affinity DataIC50:  54.6nMAssay Description:Inhibition of human factor 10A using chromogenic substrate S2222 by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed