BDBM50358908 CHEMBL1923584

SMILES COc1ccccc1-c1ccc2cnc(Nc3ccc(N4CCN(C)CC4)c(Cl)c3)nn12

InChI Key InChIKey=JQZXQAHNRZXEAP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358908   

TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50358908(CHEMBL1923584)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human recombinant JAK2 using biotinyl-amino-hexanoyl-EQEDEPEGDYFEWLE-amide as substrate after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed