BDBM50359982 CHEMBL1927771
SMILES FC(F)(F)c1cc(CC(=O)N[C@H](Cc2ccccc2)C(=O)Nc2ccc(cc2)-c2cn3c(n2)sc2ccccc32)cc(c1)C(F)(F)F
InChI Key InChIKey=WUCNRALGPZNATI-AREMUKBSSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50359982
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
University Of The Mediterranean
Curated by ChEMBL
University Of The Mediterranean
Curated by ChEMBL
Affinity DataIC50: 206nMAssay Description:Inhibition of Met-mediated scattering in HGF-stimulated human MDCK cells pre-incubated overnight prior to HGF stimulation for 24 hrs measured after 2...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of Met-triggered cell scattering in HGF-stimulated MDCK cells preincubated for overnight before HGF challenge measured after 24 to 48 hrsMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
University Of The Mediterranean
Curated by ChEMBL
University Of The Mediterranean
Curated by ChEMBL
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of Met-mediated tumorigenesis in HGF-stimulated human GTL16 cells assessed as impairment in anchorage-independent growth by soft agar grow...More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
University Of The Mediterranean
Curated by ChEMBL
University Of The Mediterranean
Curated by ChEMBL
Affinity DataIC50: 620nMAssay Description:Inhibition of Met-mediated tumorigenesis in HGF-stimulated human HepG2 cells assessed as impairment in anchorage-independent growth by soft agar grow...More data for this Ligand-Target Pair