BDBM50362286 CHEMBL1939585

SMILES CCC(CC)c1cc(C)n2nc(-c3ccc(OC)cc3Cl)n(CCO)c(=O)c12

InChI Key InChIKey=RHSHNLWTFYKAAL-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50362286   

TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50362286(CHEMBL1939585)
Affinity DataIC50:  4.40nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50362286(CHEMBL1939585)
Affinity DataEC50:  3.5nMAssay Description:Antagonist activity at human CRF1 receptor expressed in CHO-K1 cells assessed as CRF-stimulated cAMP accumulation by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed