BDBM50364032 CHEMBL1950433

SMILES COc1cc(\C=C2/CCCN3C2=NOC3(C)c2ccc(F)cc2)ccc1-n1cnc(C)c1

InChI Key InChIKey=ZBQSQLZJIGVCBL-CPNJWEJPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50364032   

TargetPresenilin-1(Homo sapiens (Human))
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50364032(CHEMBL1950433)
Affinity DataIC50:  58nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50364032(CHEMBL1950433)
Affinity DataIC50:  740nMAssay Description:Inhibition of human ERG by cell based voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed