BDBM50364034 CHEMBL1950535
SMILES COc1cc(\C=C2/CCCN3[C@H](CON=C23)c2cc(F)c(F)c(F)c2)ccc1-n1cnc(C)c1
InChI Key InChIKey=WGSSDSCDGURRHH-CRAILRFSSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50364034
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human ERG by cell based voltage clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Modulation of gamma secretase in HEK293 cells transfected with human APP with Swedish and London familial AD mutation assessed as reduction in Abeta4...More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair