BDBM50366174 CHEMBL1957605
SMILES ONC(=O)[C@@H]1CS(=O)(=O)CN1S(=O)(=O)c1ccc(cc1)-c1ccccc1
InChI Key InChIKey=VVEIZVKRPYJCPP-HNNXBMFYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50366174
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)
Curated by ChEMBL
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Inhibition of MMP9 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)
Curated by ChEMBL
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)
Curated by ChEMBL
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of MMP14 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured a...More data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)
Curated by ChEMBL
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of MMP12 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured a...More data for this Ligand-Target Pair
TargetNeutrophil collagenase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)
Curated by ChEMBL
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of MMP8 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)
Curated by ChEMBL
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of MMP1 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
TargetStromelysin-1(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)
Curated by ChEMBL
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of MMP3 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)
Curated by ChEMBL
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Inhibition of full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured after 3...More data for this Ligand-Target Pair