BDBM50366840 CHEMBL4174522

SMILES NC(=O)c1cc2ccc(cc2n1-c1cccc(CCC(O)=O)c1)C#N

InChI Key InChIKey=SCRKBSLIBXIKKM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50366840   

TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50366840(CHEMBL4174522)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of recombinant human sPLA2-2A expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGroup 10 secretory phospholipase A2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50366840(CHEMBL4174522)
Affinity DataIC50:  990nMAssay Description:Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using HDL as substrate pretreated for 20 mins followed by substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGroup 10 secretory phospholipase A2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50366840(CHEMBL4174522)
Affinity DataIC50:  110nMAssay Description:Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed