BDBM50367209 BESTATIN HYDROCHLORIDE::Ubenimex

SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O

InChI Key InChIKey=VGGGPCQERPFHOB-RDBSUJKOSA-N

Data  4 KI  1 IC50

PDB links: 26 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50367209   

TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50367209(BESTATIN HYDROCHLORIDE | Ubenimex)
Affinity DataKi:  4.10E+3nMAssay Description:Compound was evaluated for the inhibition of Aminopeptidase M (AP-M) and the inhibition constant was determined after preincubating the enzyme and in...More data for this Ligand-Target Pair
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50367209(BESTATIN HYDROCHLORIDE | Ubenimex)
Affinity DataKi:  4.10E+3nMAssay Description:Effect of inhibitor structure on the slow binding inhibition of aminopeptidase M was determined and Ki* was reported which is obtained by the equatio...More data for this Ligand-Target Pair
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50367209(BESTATIN HYDROCHLORIDE | Ubenimex)
Affinity DataKi:  7.00E+3nMAssay Description:Effect of inhibitor structure on the slow binding inhibition of aminopeptidase M was determined and the Ki was reported which is = k2/k1More data for this Ligand-Target Pair
TargetCytosol aminopeptidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50367209(BESTATIN HYDROCHLORIDE | Ubenimex)
Affinity DataKi:  2.00E+4nMAssay Description:Compound was evaluated for the inhibition of Leucine aminopeptidase and the inhibition constant was determined after preincubating the enzyme and inh...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50367209(BESTATIN HYDROCHLORIDE | Ubenimex)
Affinity DataIC50:  3.03E+3nMAssay Description:Compound was evaluated for the inhibitory activity against aminopeptidase MMore data for this Ligand-Target Pair