BDBM50375665 CHEMBL261238

SMILES CN(c1cccnc1)c1cc2c(Nc3ccc(F)c(Cl)c3)c(cnc2cn1)C#N

InChI Key InChIKey=CUIQYXHABOOZFA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50375665   

TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50375665(CHEMBL261238)
Affinity DataIC50:  50nMAssay Description:Inhibition of Tpl2 kinaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50375665(CHEMBL261238)
Affinity DataIC50: >4.00E+8nMAssay Description:Inhibition of SrcChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50375665(CHEMBL261238)
Affinity DataIC50:  5.00E+6nMAssay Description:Inhibition of EGFRChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50375665(CHEMBL261238)
Affinity DataIC50:  1.10E+8nMAssay Description:Inhibition of MK2Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed