BDBM50377067 CHEMBL427775::US8697716, 12

SMILES CN1CCN(CC1)c1ccc(NC(=O)c2ccc(o2)C#N)c(c1)C1=CCOCC1

InChI Key InChIKey=VTVVSHJUELMWBZ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50377067   

TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL

LigandBDBM50377067(CHEMBL427775 | US8697716, 12)Copy SMILESCopy InChI

Affinity DataIC50:  60nMAssay Description:Inhibition of FMSMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent

LigandBDBM50377067(CHEMBL427775 | US8697716, 12)Copy SMILESCopy InChI

Affinity DataIC50: >250nMAssay Description:The compounds of the present invention are also specific inhibitors of c-Kit. Selection of preferred compounds of Formula I for use as c-Kit inhibito...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI