BDBM50380320 CHEMBL2017653

SMILES Clc1ccc(-c2c(sc(N3CCOCC3)c2C#N)-c2nnc[nH]2)c(Cl)c1

InChI Key InChIKey=XPMQWMAEFFQIRZ-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50380320   

LigandPNGBDBM50380320(CHEMBL2017653)
Affinity DataKi:  0.350nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50380320(CHEMBL2017653)
Affinity DataKi:  2.47E+3nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50380320(CHEMBL2017653)
Affinity DataIC50:  35nMAssay Description:Inhibition of PI3Kalpha-mediated AKT phosphorylation at S473 by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed