BDBM50380541 CHEMBL2019032

SMILES Clc1ccc2c(NCCCCCCCCCCNC(=O)c3cc(=O)c4ccccc4o3)c3CCCCc3nc2c1

InChI Key InChIKey=PLKUANBZKFHKND-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50380541   

TargetBeta-secretase 1(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380541(CHEMBL2019032)
Affinity DataKi:  6.58E+3nMAssay Description:Competitive inhibition of human recombinant BChE using panvera peptide as substrate preincubated for 60 mins before substrate addition by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380541(CHEMBL2019032)
Affinity DataIC50:  0.0800nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380541(CHEMBL2019032)
Affinity DataIC50:  0.180nMAssay Description:Inhibition of horse serum BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380541(CHEMBL2019032)
Affinity DataIC50:  5nMAssay Description:Inhibition of bovine erythrocytes AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380541(CHEMBL2019032)
Affinity DataIC50:  2.24E+4nMAssay Description:Inhibition of human recombinant BChE using panvera peptide as substrate preincubated for 60 mins before substrate addition by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50380541(CHEMBL2019032)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human erythrocytes AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed