BDBM50380617 CHEMBL2016873
SMILES NC(=N)c1ccc(CNC(=O)[C@@H]2Cc3cn(Cc4cccc(Cn5cc(C[C@@H](NS(=O)(=O)Cc6ccccc6)C(=O)N2)nn5)c4)nn3)cc1
InChI Key InChIKey=BKSCOHJNKDJECO-XZWHSSHBSA-N
Data 9 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50380617
Affinity DataKi: 0.770nMAssay Description:Inhibition of plasmin by dixon plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.770nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
Affinity DataKi: 2.40nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Inhibition of plasma kallikrein by dixon plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 206nMAssay Description:Inhibition of factor 10a by dixon plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 206nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Philipps University Marburg
Curated by ChEMBL
Philipps University Marburg
Curated by ChEMBL
Affinity DataKi: 3.00E+3nMAssay Description:Inhibition of activated protein C by dixon plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 4.30E+3nMpH: 8.0Assay Description:The inhibition constants for human plasmin (h plasmin), human plasma kallikrein (h PK), thrombin and factor Xa were determined in analogy to a previo...More data for this Ligand-Target Pair
Affinity DataKi: 9.49E+3nMAssay Description:Inhibition of thrombin by dixon plot methodMore data for this Ligand-Target Pair