BDBM50380884 CHEMBL2018954
SMILES COc1ccc(COc2nc(Br)cnc2NS(=O)(=O)c2ccc(C)cc2)cc1OCCN(C)C
InChI Key InChIKey=RNYPICBYZMHNQT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50380884
Affinity DataKi: 3.16nMAssay Description:Displacement of [125I]TARC from human CCR4 expressed in CHO membranes by SPAMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Displacement of [125I]-TARC from human recombinant CCR4 expressed in CHO cell membranes by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.89nMAssay Description:Antagonist activity at human CCR4 expressed in CHO membranes assessed as inhibition of [35S]-GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Antagonist activity at human CCR4 expressed in CHO cell membranes by [35S]-GTPgammaS radioligand competition assayMore data for this Ligand-Target Pair
Affinity DataKd: 251nMAssay Description:Antagonist activity at human CCR4 in human whole blood assessed as inhibition of TARC-induced CD4+ CCR4+lymphocyte chemotaxis measuring F-actin conte...More data for this Ligand-Target Pair