BDBM50381092 CHEMBL2017552

SMILES CC(C)(O)c1ccc2cc([nH]c2c1)-c1n[nH]c2ccsc12

InChI Key InChIKey=FVSUKLKFSDSIEF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50381092   

TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381092(CHEMBL2017552)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Itk (357-620) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381092(CHEMBL2017552)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Syk (343 to 635) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381092(CHEMBL2017552)
Affinity DataIC50:  4nMAssay Description:Inhibition of [3H]-NE reuptake at Norepinephrine transporter in rat parietal/occipital cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381092(CHEMBL2017552)
Affinity DataIC50:  73.8nMAssay Description:Inhibition of Txk autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381092(CHEMBL2017552)
Affinity DataIC50:  63.9nMAssay Description:Inhibition of Lck autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed