BDBM50381714 CHEMBL2022854

SMILES Nc1ncc(-c2cnn(CCN3CCCCC3)c2)c2scc(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)c12

InChI Key InChIKey=RQYYSAWYJHRJJK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50381714   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50381714(CHEMBL2022854)
Affinity DataIC50:  4nMAssay Description:Inhibition of human KDR phosphorylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50381714(CHEMBL2022854)
Affinity DataIC50:  8nMAssay Description:Inhibition of Aurora B using 1 mM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed