BDBM50381931 CHEMBL2023476

SMILES COc1ccc2c(Oc3ccc(CC(=O)Nc4ncc(C)s4)c(OC)c3)ccnc2c1

InChI Key InChIKey=OZIZBAWFMYRHDD-UHFFFAOYSA-N

Data  4 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50381931   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

LigandBDBM50381931(CHEMBL2023476)Copy SMILESCopy InChI

Affinity DataIC50: >900nMAssay Description:Inhibition of Flt3More data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathway
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
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TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

LigandBDBM50381931(CHEMBL2023476)Copy SMILESCopy InChI

Affinity DataIC50:  20nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
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TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

LigandBDBM50381931(CHEMBL2023476)Copy SMILESCopy InChI

Affinity DataIC50:  10nMAssay Description:Inhibition of CSF-1RMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
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TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

LigandBDBM50381931(CHEMBL2023476)Copy SMILESCopy InChI

Affinity DataIC50:  0.300nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI