BDBM50386331 CHEMBL2048028

SMILES CS(=O)(=O)c1cccc(C[C@H](NC(=O)c2c(Cl)cc3CN(CCc3c2Cl)C(=O)c2ccc3ccoc3c2)C(O)=O)c1

InChI Key InChIKey=JFOZKMSJYSPYLN-QHCPKHFHSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50386331   

LigandPNGBDBM50386331(CHEMBL2048028)
Affinity DataIC50:  9nMAssay Description:Antagonist activity at LFA-1/ICAM-1 in human HuT-78 T-cells assessed as inhibition of cell adhesion after 1 hr by p-nitrophenyl n-acetyl-beta-D-gluco...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50386331(CHEMBL2048028)
Affinity DataIC50:  74nMAssay Description:Antagonist activity at LFA-1/ICAM-1 in human HuT-78 T-cells assessed as inhibition of cell adhesion after 1 hr by p-nitrophenyl n-acetyl-beta-D-gluco...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50386331(CHEMBL2048028)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50386331(CHEMBL2048028)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50386331(CHEMBL2048028)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntercellular adhesion molecule 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50386331(CHEMBL2048028)
Affinity DataIC50:  2.98nMAssay Description:Inhibition of human recombinant ICAM-1 adhesion into human Jurkat cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed