BDBM50386892 CHEMBL2048512::MMP inhibitor III
SMILES CNC(=O)C(CCc1ccccc1)NC(=O)C(CC(C)C)CC(=O)NO
InChI Key InChIKey=FQRZOEBSTPAQBJ-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50386892
TargetInterstitial collagenase [100-268](Homo sapiens (Human))
East China University of Science and Technology
East China University of Science and Technology
Affinity DataIC50: 10nMpH: 7.5Assay Description:The activity of cd-MMP-1 was measured using a fluorescence-based assay. It was performed in white 96-well half area microplate (Greiner) in a final v...More data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 8.20nMAssay Description:Inhibition of human recombinant MMP12 catalytic domain incubated for 20 mins by fluorimetric assayMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human recombinant MMP2 catalytic domain incubated for 20 mins by fluorimetric assayMore data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 4.10nMAssay Description:Inhibition of human recombinant MMP1 catalytic domain incubated for 20 mins by fluorimetric assayMore data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
East China University Of Science And Technology
Curated by ChEMBL
East China University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 6.40nMAssay Description:Inhibition of human recombinant MMP13 catalytic domain incubated for 20 mins by fluorimetric assayMore data for this Ligand-Target Pair