BDBM50387917 CHEMBL2058678::US9283222, 467
SMILES Nc1cc(Cc2n[nH]c(=O)c3CCCNc23)ccc1F
InChI Key InChIKey=FHSPZNJQUIPRJJ-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50387917
Affinity DataKi: 112nMAssay Description:Inhibition of PARP1 using [3H]NAD+ after 1 hr by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 116nMpH: 8.0Assay Description:PARP1 assay was conducted in PARP assay buffer containing 50 mM Tris pH 8.0, 1 mM DTT, 4 mM MgCl2. PARP reactions contained 1.5 uM [3H]-NAD+ (1.6 uCi...More data for this Ligand-Target Pair