BDBM50387931 CHEMBL2058912::US9283222, 708

SMILES NC1CCN(CC1)C(=O)c1cc(Cc2n[nH]c(=O)c3CCCNc23)ccc1F

InChI Key InChIKey=OIRXEJBGBNMAEY-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50387931   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM50387931(CHEMBL2058912 | US9283222, 708)
Affinity DataKi:  1.70nMpH: 8.0Assay Description:PARP1 assay was conducted in PARP assay buffer containing 50 mM Tris pH 8.0, 1 mM DTT, 4 mM MgCl2. PARP reactions contained 1.5 uM [3H]-NAD+ (1.6 uCi...More data for this Ligand-Target Pair
In DepthDetails US Patent