BDBM50389285 CHEMBL2063759
SMILES CCNC(=O)Nc1ccc(cc1)-c1nc2CCS(=O)(=O)Cc2c(n1)N1C[C@@H]2CC[C@H](C1)O2
InChI Key InChIKey=LZDMNDUELOWCFW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50389285
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: 3.00E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of mTOR-mediated AKT phosphorylation at Ser473 by cell based assayMore data for this Ligand-Target Pair