BDBM50389592 CHEMBL2069500

SMILES C1CCC(CC1)C1N[C@H](Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccccc1

InChI Key InChIKey=CMKNFFUUKQPJOF-LETIRJCYSA-N

Data  2 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50389592   

TargetSomatostatin receptor type 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50389592(CHEMBL2069500)
Affinity DataKi:  1.70nMAssay Description:Binding affinity to human SST3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50389592(CHEMBL2069500)
Affinity DataKi:  80nMAssay Description:Inhibition of MK499 binding to human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50389592(CHEMBL2069500)
Affinity DataIC50:  26nMAssay Description:Antagonist activity against human recombinant SSTR3 expressed in CHO cells assessed as reduction in forskolin-induced cAMP accumulation in presence o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50389592(CHEMBL2069500)
Affinity DataIC50:  77nMAssay Description:Displacement of [35S]MK499 from human Erg expressed in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50389592(CHEMBL2069500)
Affinity DataIC50:  0.800nMAssay Description:Displacement of [125I]SS-14 from human recombinant SSTR3 expressed in CHO cell membranes incubated for 60 to 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50389592(CHEMBL2069500)
Affinity DataIC50:  0.800nMAssay Description:Displacement of [125I]SS-14 from human SST3 receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50389592(CHEMBL2069500)
Affinity DataIC50:  26nMAssay Description:Antagonist activity at human SST3 receptor expressed in CHO cells assessed as inhibition of forskolin/SS-14-stimulated cAMP accumulation preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed