BDBM50392464 CHEMBL2151933

SMILES Cn1c(CC(=O)Nc2ccc(F)c(Br)c2)nc(cc1=O)N1CCOCC1

InChI Key InChIKey=LCPAGUVIHXELDS-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50392464   

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50392464(CHEMBL2151933)
Affinity DataIC50:  94nMAssay Description:This test is based on measuring the expression of the AKT protein phosphorylated on serine 473 (P-AKT-S473), in the PC3 human prostate carcinoma line...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM50392464(CHEMBL2151933)
Affinity DataIC50:  7.61E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50392464(CHEMBL2151933)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50392464(CHEMBL2151933)
Affinity DataIC50:  2.22E+3nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50392464(CHEMBL2151933)
Affinity DataIC50:  387nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed