BDBM50392531 CHEMBL407632
SMILES CCOc1cc(OC)ccc1C1=N[C@H]([C@H](N1C(=O)N1CCN(CCO)CC1)c1ccc(Br)cc1)c1ccc(Br)cc1
InChI Key InChIKey=PVRYEWOXWGDQHA-URLMMPGGSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50392531
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Binding affinity to MDM2 (unknown origin)More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of MDM2 binding to p53More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human GST-tagged MDM2 assessed as inhibition of binding to full length p53More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Binding affinity to MDM2 (unknown origin) expressed in Escherichia coli BL21(DE3) after 30 mins by fluorescence polarization assay in presence of P4 ...More data for this Ligand-Target Pair