BDBM50393243 CHEMBL2151437

SMILES C1c2cccnc2O[C@]11CN2CCC1CC2

InChI Key InChIKey=OCKIPDMKGPYYJS-ZDUSSCGKSA-N

Data  5 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50393243   

TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Targacept

Curated by ChEMBL
LigandPNGBDBM50393243(CHEMBL2151437)
Affinity DataKi:  3nMAssay Description:Binding affinity to human alpha7 nAchRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Targacept

Curated by ChEMBL
LigandPNGBDBM50393243(CHEMBL2151437)
Affinity DataKi:  3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR expressed in HEK293 cell membranes after 2 hrs by topcount scintillation counting an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50393243(CHEMBL2151437)
Affinity DataKi:  5nMAssay Description:Displacement of [125I]alpha-bungarotoxin from rat alpha7 nAChR expressed in HEK293 cell membranes after 2 hrs by topcount scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Targacept

Curated by ChEMBL
LigandPNGBDBM50393243(CHEMBL2151437)
Affinity DataKi:  12nMAssay Description:Binding affinity to human 5HT3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Targacept

Curated by ChEMBL
LigandPNGBDBM50393243(CHEMBL2151437)
Affinity DataKi:  140nMAssay Description:Binding affinity to human alpha4beta2 nAChRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Targacept

Curated by ChEMBL
LigandPNGBDBM50393243(CHEMBL2151437)
Affinity DataEC50:  340nMAssay Description:Agonist activity at human alpha7 nAChRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed