BDBM50394517 CHEMBL2160173

SMILES COCCN(CC(C)C)c1ccc(OC)c2nc(c(C)cc12)-c1c(OC)cc(COC)cc1OC

InChI Key InChIKey=HAWIDCANNJBIHK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50394517   

TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50394517(CHEMBL2160173)
Affinity DataIC50:  156nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50394517(CHEMBL2160173)
Affinity DataIC50:  65nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-induced intracellular cAMP production preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed