BDBM50395775 CHEMBL2164857

SMILES CNc1cc(ccn1)-c1nnc(NC(=O)[C@H](Cc2ccccc2)NCc2cscn2)s1

InChI Key InChIKey=BQOUXRFZMULETF-KRWDZBQOSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50395775   

TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50395775(CHEMBL2164857)
Affinity DataEC50:  36nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProbable G-protein coupled receptor 142(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50395775(CHEMBL2164857)
Affinity DataIC50:  15nMAssay Description:Partial agonist activity at mouse GPR142 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed