BDBM50396238 CHEMBL2172212::US9402842, 62
SMILES NCCCn1c2-c3ccccc3C(=O)c2c2ccc(N)cc2c1=O
InChI Key InChIKey=AEJWFHDNVYSNLA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50396238
Affinity DataIC50: 1.20E+4nMpH: 7.5 T: 2°CAssay Description:Tdp1 reactions were performed as recently described. Briefly, a 5'-[32P]-labeled single-stranded DNA oligonucleotide containing a 3'-phosphotyrosine ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMpH: 7.5 T: 2°CAssay Description:A 5′-[32P]-labeled single-stranded DNA oligonucleotide containing a 3′-phosphotyrosine (N14Y) was generated as described by Dexheimer et ...More data for this Ligand-Target Pair
Affinity DataEC50: 4.40E+3nMAssay Description:Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate...More data for this Ligand-Target Pair
Affinity DataEC50: 3.37E+3nMAssay Description:Agonist activity at human RXRalpha expressed in african green monkey COS1 cells assessed as induction of RXRE transcriptional activity after 12 hrs b...More data for this Ligand-Target Pair