BDBM50398078 CHEMBL2182019

SMILES CCCCNC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)Cc1ccc2ccccc2c1)[C@@H](C)CC

InChI Key InChIKey=VJOMUGCLHKOLJU-QLADTWODSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50398078   

TargetNeutrophil elastase(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50398078(CHEMBL2182019)
Affinity DataKi:  1.80E+4nMAssay Description:Noncompetitive inhibition of human neutrophil elastase assessed as hydrolysis of N-succinyl-Ala-Ala-Pro-Val-p-nitroanilide incubated for 2 hrs measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50398078(CHEMBL2182019)
Affinity DataIC50:  9.90E+4nMAssay Description:Inhibition of plasmin assessed as hydrolysis of H-D-Val-L-Leu-L-Lys-p-nitroanilide incubated for 2 hrs measured for 20 mins by microplate reader anal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50398078(CHEMBL2182019)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human neutrophil elastase assessed as hydrolysis of N-succinyl-Ala-Ala-Pro-Val-p-nitroanilide incubated for 2 hrs measured for 20 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50398078(CHEMBL2182019)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of thrombin assessed as hydrolysis of H-D-Pro-L-Phe-L-Arg-p-nitroanilide incubated for 2 hrs measured for 20 mins by microplate reader ana...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed