BDBM50399434 CHEMBL2179387

SMILES COc1ccccc1S(=O)(=O)Nc1ccc2NC(=O)N(C)Cc2c1

InChI Key InChIKey=TXZPMHLMPKIUGK-UHFFFAOYSA-N

Data  14 IC50  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50399434   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50399434(CHEMBL2179387)
Affinity DataIC50:  220nMAssay Description:Binding affinity to human BRD4 bromodomain 1 using H4Ac4 peptide by amplified luminescent proximity homogeneous assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50399434(CHEMBL2179387)
Affinity DataIC50:  220nMAssay Description:Inhibition of recombinant His-tagged human BRD4 bromodomain 1 expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells preincubated for 30 mins follow...More data for this Ligand-Target Pair