BDBM50399470 CHEMBL2179784

SMILES Nc1ncnc2n(nc(-c3cccc(c3)C(=O)NCc3ccccc3)c12)[C@@H]1CCCN(C1)C(=O)C=C

InChI Key InChIKey=ZDTBVPXHUPZUQP-OAQYLSRUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50399470   

TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50399470(CHEMBL2179784)
Affinity DataIC50:  8.80E+3nMAssay Description:Covalent inhibition of ITK in presence of 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50399470(CHEMBL2179784)
Affinity DataIC50:  2.45E+3nMAssay Description:Covalent inhibition of ITK in presence of 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed