BDBM50399471 CHEMBL2179781
SMILES CC(C)c1ccc(NC(=O)c2cccc(c2)-c2nn([C@@H]3CCCN(C3)C(=O)C#C)c3ncnc(N)c23)cc1
InChI Key InChIKey=MMTIMKJVYCMIOF-HSZRJFAPSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50399471
Affinity DataIC50: 10nMAssay Description:Covalent inhibition of ITK in presence of 1 mM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Covalent inhibition of ITK in human Jurkat cells assessed as inhibition of anti-CD3 antibody-stimulated PLCgamma phosphorylation pre-incubated before...More data for this Ligand-Target Pair