BDBM50404020 CHEMBL435324::MEN-11558

SMILES O=C1CCC(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2ccccc2)CN1

InChI Key InChIKey=PRRYSNSLFNBYDL-IGBKUBFESA-N

Data  4 KI  8 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50404020   

TargetSubstance-K receptor(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50404020(CHEMBL435324 | MEN-11558)
Affinity DataKi:  2nMAssay Description:Binding affinity towards Tachykinin receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50404020(CHEMBL435324 | MEN-11558)
Affinity DataKd:  34nMAssay Description:Compound was evaluated for Kd value against [125I]NKA on the Tyr266Phe mutated human NK-2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50404020(CHEMBL435324 | MEN-11558)
Affinity DataKd:  1.30nMAssay Description:Compound was evaluated for Kd value against [3H]-SR- 48968 on the Tyr206Phe mutated human NK-2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50404020(CHEMBL435324 | MEN-11558)
Affinity DataKd:  1.96E+3nMAssay Description:Compound was evaluated for Kd value against [3H]-SR- 48968 on the Tyr206Ala mutated human NK-2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50404020(CHEMBL435324 | MEN-11558)
Affinity DataKd:  3.60nMAssay Description:Compound was evaluated for Kd value against [125I]NKA on the Tyr206Phe mutated human NK-2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50404020(CHEMBL435324 | MEN-11558)
Affinity DataKd:  2.70nMAssay Description:Compound was evaluated for Kd value against [125I]NKA on the Wild-type tachykinin receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50404020(CHEMBL435324 | MEN-11558)
Affinity DataKd:  208nMAssay Description:Compound was evaluated for Kd value against [3H]-SR- 48968 on the Phe270Ala mutated human NK-2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50404020(CHEMBL435324 | MEN-11558)
Affinity DataKd:  10nMAssay Description:Compound was evaluated for Kd value against [3H]-SR- 48968 on the Wild-type tachykinin receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50404020(CHEMBL435324 | MEN-11558)
Affinity DataKd:  48nMAssay Description:Compound was evaluated for Kd value against [3H]-SR- 48968 on the Tyr266Phe mutated human NK-2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed