BDBM50413752 CHEMBL2012519::L-783277
SMILES COc1cc(O)c2c(CCCC(=O)C(=O)C(O)CCC[C@H](C)OC2=O)c1
InChI Key InChIKey=CZVAYVPOBIDGLC-ZSOXZCCMSA-N
Data 47 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 35 hits for monomerid = 50413752
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of EPHB4 by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 640nMAssay Description:Inhibition of MK5 by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of RET by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of TYK2 by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 950nMAssay Description:Inhibition of ERK2 by Caliper mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Aurora A kinase by Caliper mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Axl by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BTK by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ZAP70 by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of EPHA4 by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HGFR by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of IGF1R by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of JAK1 by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of JAK2 by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of JAK3 by Caliper mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PKN1 by Caliper mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PKN2 by Caliper mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ROCK2 by Caliper mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 763nMAssay Description:Inhibition of ALK by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of INSR by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of MEK2 by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of VEGFR2 by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of p38alpha by Caliper mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDK2A by Caliper mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HER2 by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PKAalpha by Caliper mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 303nMAssay Description:Inhibition of cKIT by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GSK3-beta by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDK1 by Caliper mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR3 by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Inhibition of VEGFR2 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant FLT3 ITD mutant (unknown origin) by RBC kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Inhibition of recombinant FLT3 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant FLT3 D835Y mutant (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of LCK by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair