BDBM50414446 CHEMBL539730

SMILES CC(C)(C)C(=O)Nc1ccc(N2CCN(CC2)C(=O)c2ccccc2)c(Cl)c1

InChI Key InChIKey=IKZIGILJXHWDKK-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50414446   

TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50414446(CHEMBL539730)
Affinity DataKi:  501nMAssay Description:Antagonist activity at human NPY Y2 receptor in KAN-TS cells by [35]GTPgammaS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50414446(CHEMBL539730)
Affinity DataKi:  501nMAssay Description:Antagonist activity at human neuropeptide Y2 receptor in KAN-TS cells by [35]GTPgammaS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50414446(CHEMBL539730)
Affinity DataKi: >5.01E+3nMAssay Description:Antagonist activity at human neuropeptide Y5 receptor expressed in HEK293 cells by FLIPR/Ca2+ methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50414446(CHEMBL539730)
Affinity DataKi: >6.31E+3nMAssay Description:Antagonist activity at human neuropeptide Y1 receptor expressed in CHO cells by [35]GTPgammaS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed