BDBM50414468 CHEMBL1196581::CHEMBL557502

SMILES COc1cccnc1C(=O)N1CCN(CC1)c1ccc(NC(=O)C(C)(C)c2ccccc2)cc1Cl

InChI Key InChIKey=WIHRUDKZTYLJLT-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50414468   

TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50414468(CHEMBL1196581 | CHEMBL557502)
Affinity DataKi:  25.1nMAssay Description:Antagonist activity at human NPY Y2 receptor in KAN-TS cells by [35]GTPgammaS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50414468(CHEMBL1196581 | CHEMBL557502)
Affinity DataKi:  25.1nMAssay Description:Antagonist activity at human neuropeptide Y2 receptor in KAN-TS cells by [35]GTPgammaS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y-Y2 receptor(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50414468(CHEMBL1196581 | CHEMBL557502)
Affinity DataKi:  50.1nMAssay Description:Antagonist activity at rat NPY Y2 receptor expressed in HEK cells by [35]GTPgammaS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50414468(CHEMBL1196581 | CHEMBL557502)
Affinity DataKi: >6.31E+3nMAssay Description:Antagonist activity at human neuropeptide Y1 receptor expressed in CHO cells by [35]GTPgammaS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50414468(CHEMBL1196581 | CHEMBL557502)
Affinity DataKi: >1.00E+4nMAssay Description:Antagonist activity at human neuropeptide Y5 receptor expressed in HEK293 cells by FLIPR/Ca2+ methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50414468(CHEMBL1196581 | CHEMBL557502)
Affinity DataIC50:  5.01E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed