BDBM50414968 CHEMBL410885
SMILES O=C(N1CCC2(CCN(Cc3cccc(Oc4ccccc4)c3)CC2)CC1)c1ccncn1
InChI Key InChIKey=GDZWYFZOGVMUEB-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50414968
Affinity DataIC50: 28nMAssay Description:Antagonist activity at CCR8 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 27.5nMAssay Description:Antagonist activity at human CCR8More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of wild type human ERG expressed in CHOK1 cells by whole-cell plate-based electrophysiologyMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 1.41E+3nMAssay Description:Displacement of [3H]dofetilide from human recombinant ERG expressed in HEK293 cells by patch clamp methodMore data for this Ligand-Target Pair