BDBM50420312 CHEMBL2089109

SMILES Cc1c(Cn2c(nc(=O)c3sc(nc23)N2CCOCC2)C2CC2)cccc1C(F)(F)F

InChI Key InChIKey=PXKXPHKDCJBQCI-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50420312   

LigandPNGBDBM50420312(CHEMBL2089109)
Affinity DataEC50:  9nMAssay Description:Inhibition of PI3K beta in human PTEN-deficient MDA-MB-468 cells assessed as inhibition of Akt Ser473 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50420312(CHEMBL2089109)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of PI3K gamma by continuous TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50420312(CHEMBL2089109)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of PI3K alpha by continuous TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50420312(CHEMBL2089109)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of PI3K beta by continuous TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50420312(CHEMBL2089109)
Affinity DataIC50:  16nMAssay Description:Inhibition of PI3K delta by continuous TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed