BDBM50420677 CHEMBL2087057

SMILES CC(C)c1ccc(C)cc1C(=O)NCCc1ccccc1

InChI Key InChIKey=DWLZUEABXCINMW-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50420677   

TargetTransient receptor potential cation channel subfamily M member 8(Rattus norvegicus (Rat))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50420677(CHEMBL2087057)
Affinity DataIC50:  320nMAssay Description:Inhibition of rat TRPM8 expressed in HEK293 cells assessed as reduction in 20 uM menthol-stimulated increase in intracellular Ca2+ levelsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily M member 8(Rattus norvegicus (Rat))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50420677(CHEMBL2087057)
Affinity DataIC50:  600nMAssay Description:Inhibition of rat TRPM8 expressed in HEK293 cells assessed as reduction in 0.25 uM icilin-stimulated increase in intracellular Ca2+ levelsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50420677(CHEMBL2087057)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of rat TRPA1 expressed in HEK293 cells assessed as reduction in 100 uM allyl isothiocyanate-stimulated increase in intracellular Ca2+ leve...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily M member 8(Rattus norvegicus (Rat))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50420677(CHEMBL2087057)
Affinity DataEC50:  270nMAssay Description:Activation of rat TRPM8 expressed in HEK293 cells assessed as stimulation of intracellular Ca2+ levelsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed