BDBM50422013 LOBELINE::Lobeline Hydrochloride

SMILES CN1[C@@H](C[C@H](O)c2ccccc2)CCC[C@H]1CC(=O)c1ccccc1

InChI Key InChIKey=MXYUKLILVYORSK-HKBOAZHASA-N

Data  10 KI  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50422013   

TargetHistamine H1 receptor(RAT)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50422013(LOBELINE | Lobeline Hydrochloride)
Affinity DataIC50:  1.12E+4nMAssay Description:Displacement of [3H]mepyramine from histamine H1 receptor in Sprague-Dawley rat brain membrane after 2 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50422013(LOBELINE | Lobeline Hydrochloride)
Affinity DataIC50:  4.47E+4nMAssay Description:Antagonist activity at H1 receptor in human HeLa cells assessed as inhibition of histamine-induced Ca2+ release by using fura-2AM-based fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed