BDBM50424075 (-)-Corydalmine::CHEMBL448891
SMILES COc1cc2CCN3Cc4c(C[C@H]3c2cc1OC)ccc(O)c4OC
InChI Key InChIKey=DIHXHTWYVOYYDC-INIZCTEOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50424075
Affinity DataKi: 50nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor (unknown origin) expressed in human HEK293 cells by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 107nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor after 1 hrMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 149nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-HT1A receptor (unknown origin) expressed in HEK293 cells by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 242nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D5 receptor after 1 hrMore data for this Ligand-Target Pair
Affinity DataKi: 305nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor (unknown origin) expressed in human HEK293 cells by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 533nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D2 receptor after 1 hrMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D4 receptor after 1 hrMore data for this Ligand-Target Pair
Affinity DataKi: 1.71E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor after 1 hrMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Sunchon National University
Curated by ChEMBL
Sunchon National University
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of recombinant human MAO-B using benzylamine as substrate incubated for 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Sunchon National University
Curated by ChEMBL
Sunchon National University
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of recombinant human MAO-A using kynuramine as substrate incubated for 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataEC50: 1.35E+3nMAssay Description:Agonist activity at dopamine D1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding by scintillatio...More data for this Ligand-Target Pair
Affinity DataIC50: 2.13E+4nMAssay Description:Antagonist activity at dopamine D1 receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of [35S]GTPgammaS binding by scintillat...More data for this Ligand-Target Pair
Affinity DataIC50: 1.87E+4nMAssay Description:Antagonist activity at dopamine D2 receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of [35S]GTPgammaS binding by scintillat...More data for this Ligand-Target Pair
Affinity DataIC50: 152nMAssay Description:Inhibition of tissue factor procoagulant activity in LPS-stimulated human THP1 cells preincubated for 1 hr before LPS addition measured after 5 hrsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataEC50: 190nMAssay Description:Agonist activity at 5-HT1A receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of [35S]GTPgammaS binding by scintillation prox...More data for this Ligand-Target Pair